JOURNAL PUBLICATIONS

Spectral contrast imaging microscopy

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August 19, 2011
Opt. Lett.; 36: 3323-3325 (2011).
S. Alexandrov, S. Uttam, R. Bista, and Y. Liu

We introduce a new technique, spectral contrast imaging microscopy (SCIM), for super-resolution microscopic imaging. Based on a novel contrast mechanism that encodes each local spatial frequency with a corresponding optical wavelength, SCIM provides a real-time high-resolution spectral contrast microscopic image with superior contrast. We show that two microscopic objects, separated by a distance smaller than the diffraction limit of the optical system, can be spatially resolved in the SCIM image as different colors. Results with numerical simulation and experiments using a high-resolution United States Air Force target are presented. The ability of SCIM for imaging biological cells is also demonstrated.

https://doi.org/10.1364/OL.36.003323