Semester: Spring 2025
This course will introduce students to micron, nanometer, and sub-nanometer scale imaging-based approaches in experimental, computational and systems biology. Emphasis will be placed on understanding the fundamentals of image formation, processing, and analysis of brightfield, phase-contrast, highly multiplexed, super-resolution, live-cell, cryo-EM, and computational imaging, along with imaging-based spatial transcriptomic methods. Applications of these methods in studying biological phenomena in space and time will also be discussed. Python will be the programming language in which image processing, machine learning, and system biology methods introduced in the course will be implemented. Students are expected to know Python basics. It is also expected that students have a basic understanding of linear algebra and calculus.