Gastrointestinal Endoscopy; 95(6):1239-1246 (2022).
We utilized the ability of nanoscale nuclear architecture mapping (nanoNAM) to detect with nanoscale sensitivity, structural alterations in the chromatin of epithelial cell nuclei at risk for malignant transformation, to identify patients with Barrett’s esophagus (BE) who progress to high grade dysplasia (HGD) or esophageal adenocarcinoma (EAC).
